Human / Cynomolgus Activin RIIA / ACVR2A Protein, His Tag (MALS & SPR verified), Unconjugated

Artikelnummer: ABS-ACA-H5243-1MG
Artikelname: Human / Cynomolgus Activin RIIA / ACVR2A Protein, His Tag (MALS & SPR verified), Unconjugated
Artikelnummer: ABS-ACA-H5243-1MG
Hersteller Artikelnummer: ACA-H5243-1mg
Alternativnummer: ABS-ACA-H5243-1MG
Hersteller: AcroBiosystems
Wirt: Human
Kategorie: Proteine/Peptide
Spezies Reaktivität: Human, Monkey
Konjugation: Unconjugated
Activin receptor type2A (ACVR2A) is also known as Activin receptor type IIA, ACTRIIA, ACTRIIA and ACVR2,which is singlepass type I membrane protein. ACVR2A belongs to the protein kinase superfamily,TKL Ser/Thr protein kinase family and TGFB receptor subfamily.On ligand binding,ACVR2A can forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators.ACVR2A is Receptor for activin A, activin B and inhibin A as well. Several type I I activin receptors have been identified and bind to different activins with different affinities. - Proteine/Peptide
Molekulargewicht: 15.4 kDa
Tag: N-10*His
NCBI: 27037
Puffer: PBS, pH7.4
Reinheit: 90%
Formulierung: Powder
Target-Kategorie: Activin RIIA
Immobilized Human / Cynomolgus Activin RIIA Protein, His Tag (Cat. No. ACA-H5243) at 1 µg/mL (100 µL/well) can bind Bimagrumab with a linear range of 0.05-1 ng/mL (Routinely tested).
Human / Cynomolgus Activin RIIA Protein, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.
ACA-H5243-1mg