Canine Growth Hormone R (GHR) Protein, His Tag, Unconjugated, Human
Artikelnummer:
ABS-GHR-C52H9-1MG
Hersteller Artikelnummer:
GHR-C52H9-1mg
Alternativnummer:
ABS-GHR-C52H9-1MG
Hersteller:
AcroBiosystems
Wirt:
Human
Kategorie:
Proteine/Peptide
Spezies Reaktivität:
Canine
Konjugation:
Unconjugated
Growth hormone receptor (GHR) is also known as somatotropin receptor, growth hormonebinding protein (GHBR), which belongs to the type I cytokine receptor family or Type 1 subfamily. GHR contains one fibronectin typeIII domain. GHR / GHBR is expressed in various tissues with high expression in liver and skeletal muscle. The soluble form (GHBP) is produced by phorbol esterpromoted proteolytic cleavage at the cell surface (shedding) by ADAM17/TACE. GHR is receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to the JAK2/STAT5 pathway. The soluble form (GHBP) acts as a reservoir of growth hormone in plasma and may be a modulator/inhibitor of GH signaling. - Proteine/Peptide
