Fm-479 was a negative control of FM-381 (HY-102046) and showed no activity against JAK3 or other kinases. Fm-381 is a potent covalent reversible inhibitor of JAK3 targeting unique Cys909. For JAK3, FM-381 was 410, 2700 and 3600 times more selective than
Molekulargewicht:
442.51
CAS Nummer:
[2226521-64-6]
Formel:
C25H26N6O2
Target-Kategorie:
JAK
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