E.coli-derived human IKB alpha recombinant protein (Position: Q3-Q112). Human IKB alpha shares 87% and 86% amino acid (aa) sequence identity with mouse and rat IKB alpha, respectively.
Alternative Synonym:
EDAID2,IkappaBalpha,I-kappa-B-alpha,IKBA,ikB-alpha,MAD-3,major histocompatibility complex enhancer-binding protein MAD3,NF-kappa-B inhibitor alpha,NFKBI,nuclear factor of kappa light chain gene enhancer in B-cells,nuclear factor of kappa light polypeptid
Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubi
