E.coli-derived human PKC iota recombinant protein (Position: D21-Q214). Human PKC iota shares 96% and 97% amino acid (aa) sequence identity with mouse and rat PKC iota, respectively.
Alternative Synonym:
aPKC-lambda/iota,atypical protein kinase C-lambda/iota,DXS1179E,nPKC-iota,PKCI,PRKC-lambda/iota,protein kinase C iota type.
Calcium- and diacylglycerol-independent serine/ threonine-protein kinase that plays a general protective role against apoptotic stimuli, is involved in NF-kappa-B activation, cell survival, differentiation and polarity, and contributes to the regulation