E.coli-derived human TCPTP recombinant protein (Position: M1-C330). Human TCPTP shares 91.4% and 92% amino acid (aa) sequence identity with mouse and rat TCPTP, respectively.
Alternative Synonym:
PTN2,PTPT,T-cell protein tyrosine phosphatase,T-cell protein-tyrosine phosphatase,TCELLPTP,TCPTP,TC-PTP,tyrosine-protein phosphatase non-receptor type 2.
Non-receptor type tyrosine-specific phosphatase that dephosphorylates receptor protein tyrosine kinases including INSR, EGFR, CSF1R, PDGFR. Also dephosphorylates non-receptor protein tyrosine kinases like JAK1, JAK2, JAK3, Src family kinases, STAT1, STAT
