GC-binding transcription factor Sp3,specificity protein 3,SPR2,SPR-2,transcription factor Sp3.
Transcriptional factor that can act as an activator or repressor depending on isoform and/or post-translational modifications. Binds to GT and GC boxes promoter elements. Competes with SP1 for the GC-box promoters. Weak activator of transcription but can