Recombinant Human Tumor necrosis factor alpha-induced protein 8 protein (1-198AA)
Konjugation:
Unconjugated
Alternative Synonym:
GG2-1,head and neck tumor and metastasis-related protein,MDC-3.13,NDED,NF-kappa-B-inducible DED-containing protein,SCCS2,SCC-S2,TNF-induced protein GG2-1,tumor necrosis factor alpha-induced protein 8,tumor necrosis factor, alpha induced protein 8.
Acts as a negative mediator of apoptosis and may play a role in tumor progression. Suppresses the TNF-mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8, subsequently resulting in inhibition of BID cleavage and cas