Recombinant Human F-box/LRR-repeat protein 5 protein (1-310AA)
Konjugation:
Unconjugated
Alternative Synonym:
FBL4,FBL5,F-box and leucine-rich repeat protein 5,F-box protein FBL4/FBL5,F-box/LRR-repeat protein 5,FLR1,p45SKP2-like protein.
Component of some SCF (SKP1-cullin-F-box) protein ligase complex that plays a central role in iron homeostasis by promoting the ubiquitination and subsequent degradation of IREB2/IRP2. Upon high iron and oxygen level, it specifically recognizes and binds