Recombinant Human F-box only protein 22 protein (104-403AA)
Konjugation:
Unconjugated
Alternative Synonym:
F-box only protein 22,F-box protein FBX22p44,FBX22,FIST domain containing 1,FISTC1.
Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Promotes the proteasome-dependent degradation of key sarcomeric proteins, such as alpha-actinin (ACTN2) and filamin-C (FLNC), essential for maintenance