CD161,CLEC5B,C-type lectin domain family 5 member B,hNKR-P1A,killer cell lectin-like receptor subfamily B member 1,killer cell lectin-like receptor subfamily B, member 1,natural killer cell surface protein P1A,NKR,NKR-P1,NKRP1A,NKR-P1A.
Plays an inhibitory role on natural killer (NK) cells cytotoxicity. Activation results in specific acid sphingomyelinase/SMPD1 stimulation with subsequent marked elevation of intracellular ceramide. Activation also leads to AKT1/PKB and RPS6KA1/RSK1 kina