dual specificity mitogen-activated protein kinase kinase 3,MAP kinase kinase 3,MAPK/ERK kinase 3,MAPKK 3,MAPKK3,MEK 3,MEK3,MKK3,PRKMK3,SAPK kinase 2,SAPKK2,SAPKK-2,stress-activated protein kinase kinase 2.
Dual specificity kinase. Is activated by cytokines and environmental stress in vivo. Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in the MAP kinase p38. Part of a signaling cascade that begins with the activation of the