IIAE6,MyD88-3,proline-rich, vinculin and TIR domain-containing protein B,PRVTIRB,putative NF-kappa-B-activating protein 502H,TICAM-1,TIR domain containing adaptor inducing interferon-beta,TIR domain-containing adapter molecule 1,TIR domain-containing ada
Involved in innate immunity against invading pathogens. Adapter used by TLR3 and TLR4 (through TICAM2) to mediate NF-kappa-B and interferon-regulatory factor (IRF) activation, and to induce apoptosis. Ligand binding to these receptors results in TRIF rec