FLASH antibody was raised against a synthetic peptide corresponding to amino acids near the carboxy terminus of human FLASH which differ from those of mouse by one amino acid. The immunogen is located within the last 50 amino acids of FLASH.
Konjugation:
Unconjugated
Alternative Synonym:
CASP8-associated protein 2,CED-4,FLASH,FLASH homolog RIP25,FLICE associated huge,FLICE-associated huge protein,human FLASH,RIP25.
Participates in TNF-alpha-induced blockade of glucocorticoid receptor (GR) transactivation at the nuclear receptor coactivator level, upstream and independently of NF-kappa-B. Suppresses both NCOA2- and NCOA3-induced enhancement of GR transactivation. In
