TLR11 antibody was raised against a peptide corresponding to 15 amino acids near the carboxy terminus of mouse TLR11. The immunogen is located within the last 50 amino acids of TLR11.
Participates in the innate immune response to microbial agents. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.