Anti-PD-L2 antibody (4063) was raised against a peptide corresponding to 16 amino acids near the center of human PD-L2. The immunogen is located within amino acids 140-190 of PD-L2.
Konjugation:
Unconjugated
Alternative Synonym:
B7 dendritic cell molecule,B7DC,B7-DC,bA574F11.2,Btdc,butyrophilin B7-DC,CD273,PD-1-ligand 2,PDCD1 ligand 2,PDCD1L2,PDL2,PD-L2,programmed cell death 1 ligand 2,programmed death ligand 2.
Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production (By similarity).