Synthesized peptide derived from human Akt1 around the phosphorylation site of T450. Location: 390-470aa.
Alternative Synonym:
AKT, PKB, RAC, PRKBA, PKB-ALPHA, RAC-ALPHA
The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific,