Synthesized peptide derived between 91-140 amino acids from the N-terminal region of human CD71.
Alternative Synonym:
T9, TR, TFR, p90, CD71, TFR1, TRFR, IMD46
Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface w