DED, BFR2, CHE1, CHE-1, Protein AATF, Apoptosis-antagonizing transcription factor, Rb-binding protein Che-1, AATF, HSPC277
May function as a general inhibitor of the histone deacetylase HDAC1. Binding to the pocket region of RB1 may displace HDAC1 from RB1/E2F complexes, leading to activation of E2F target genes and cell cycle progression. Conversely, displacement of HDAC1 f