IL-6mediates its biological effects through the type IIL-6receptor system that consists of two chains, IL-6Ralpha and gp130. While the IL-6Ralpha chain is the binding component specific to IL-6, the gp130 chain only transmits signals of IL-6when bound to IL-
Centrifuge the vial prior to opening. Reconstitute in 1× PBS, pH 7.2 to a concentration of 0.1–1.0 mg/ml. Do not vortex. This solution can be stored at 2–8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer...
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