Synthetic phosphopeptide derived from human IRS-1 around the phosphorylation site of Serine 794.
Konjugation:
Unconjugated
Alternative Synonym:
Insulin receptor substrate 1, IRS-1, IRS1
Insulin receptor substrate 1 (IRS-1) is one of the major substrates of the insulin receptor kinase. IRS-1 contains multiple tyrosine phosphorylation motifs that serve as docking sites for SH2-domain containing proteins that mediate the metabolic and grow
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Formulierung:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.3.
Application Verdünnung:
WB: 1:500~1:1000
Anwendungsbeschreibung:
IRS-1 (Phospho-Ser794) polyclonal antibody detects endogenous levels of IRS-1 protein only when phosphorylated at Ser794.
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