Caspase-8 (T341) polyclonal antibody, Unconjugated, Rabbit

Artikelnummer: BWT-AP0358
Artikelname: Caspase-8 (T341) polyclonal antibody, Unconjugated, Rabbit
Artikelnummer: BWT-AP0358
Hersteller Artikelnummer: AP0358
Alternativnummer: BWT-AP0358-50UL,BWT-AP0358-100UL
Hersteller: Bioworld Technology
Wirt: Rabbit
Kategorie: Antikörper
Applikation: IHC, WB
Spezies Reaktivität: Human, Mouse, Rat
Immunogen: Synthetic peptide, corresponding to amino acids 310-362 of Human Caspase-8.
Konjugation: Unconjugated
Alternative Synonym: Caspase-8, Caspase8, Caspase 8, CASP-8, Apoptotic cysteine protease, Apoptotic protease Mch-5, CAP4, FADD-homologous ICE/ced-3-like protease, FADD-like ICE, FLICE, ICE-like apoptotic protease 5, MORT1-associated ced-3 homolog, MACH, Caspase-8 subunit p18
Caspases are cysteine proteases, expressed as inactive precursors, that mediate apoptosis by proteolysis of specific substrates. Caspases have the ability to cleave after aspartic acid residues. There are two classes of caspases involved in apoptosis, in
Molekulargewicht: ~ 18, 38, 55 kDa
UniProt: Q14790
Reinheit: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Formulierung: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Application Verdünnung: WB: 1:500~1:1000 IHC: 1:50~1:200
Anwendungsbeschreibung: Caspase 8 (T341) polyclonal antibody detects endogenous levels of full length caspase-8, the cleaved intermediate p43/p41 and the caspase-8 active fragment p18.