ssPalmE-P4C2

Produktübersicht

• Artikelname: ssPalmE-P4C2
• Artikelnummer: ECH-N-1019-5MG
• Hersteller Artikelnummer: N-1019-5MG
• Alternativnummer: ECH-N-1019-5MG
• Hersteller: Echelon Biosciences
• Kategorie: Molekularbiologie

Produktbeschreibung

ssPalmE-P4C2 is an ionizable lipid with a Vitamin E scaffold that is used to formulate lipid nanoparticles (LNPs) for delivering RNA into cells.

Zusatzinformationen

Background

ssPalmE-P4C2 is an ionizable lipid with a Vitamin E scaffold that is used to formulate lipid nanoparticles (LNPs) for delivering RNA into cells. The Vitamin E scaffold acts as an adjuvant to activate innate immune signaling. Vaccination with ssPalmE-P4C2 containing LNPs protected against lethal infection by Toxoplasma gondii in a mouse model.

References

R. Oyama et al, “An ionizable lipid material with a Vitamin E scaffold as an mRNA vaccine platform for efficient cytotoxic T cell responses” ACS Nano 2023, 17, 18758-18775

 

Additional Information

Molecular Formula: C84H140N2O10S2

MW: 1402.17

CAS: n/a

Alternative Names: O,O'-(((disulfanediylbis(ethane-2,1-diyl))bis(piperidine-1,4-diyl))bis(ethane-2,1-diyl)) bis(2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)chroman-6-yl) disuccinate

Solubility: ~5 mg/mL in ethanol, >10 mg/mL dichloromethane.

Storage and Handling: Store dry at -20 0C. Stock solution should be stored frozen (-20 0C or below)

Bilder

ECH-N-1019