BMS-5 is a potent inhibitor of the LIM kinase. It has IC50 values of 7nM and 8 nM for LIMK1 and LIMK2 respectively. LIMK1/2 activity was measured via TCA precipitation assay using a biotinylated ADF (actin depolymization factor) as the protein substrate
Molekulargewicht:
431.3
Reinheit:
98% (HPLC)
CAS Nummer:
[1338247-35-0]
Formel:
C17H14Cl2F2N4OS
Target-Kategorie:
LIMK1, LIMK2
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten