AZD8055 is a novel ATP-competitive inhibitor of mTOR kinase activity with an IC50 of 0.8 nM. It shows excellent selectivity (~1,000-fold) against all class I phosphatidylinositol 3-kinase (PI3K) isoforms and other members of the PI3K-like kinase family.
Molekulargewicht:
465.5
Reinheit:
98% (HPLC)
CAS Nummer:
[1009298-09-2]
Formel:
C25H31N5O4
Target-Kategorie:
mTOR, PI3 kinase
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