Momelotinib

Artikelnummer: ENZ-ENZ-CHM197-0001
Artikelname: Momelotinib
Artikelnummer: ENZ-ENZ-CHM197-0001
Hersteller Artikelnummer: ENZ-CHM197-0001
Alternativnummer: ENZ-ENZ-CHM197-0001-1
Hersteller: Enzo Life Sciences
Kategorie: Sonstiges
Alternative Synonym: CYT 387, N-(cyanomethyl)-4-[2-[[4-(4-morpholinyl)phenyl]amino]-4-pyrimidinyl]-benzamide
Using ATP kinase assays, the IC50 values for CYT387 are a follows - JAK1 (11nM), JAK2, (18nM), JAK2 V617F (23nM) JAK3 (155nM), and TYK2 (17nM). In testing kinase arrays, CYT387 also had activity (defined as an IC50 < 100nM) detected against CDK2/cyclin A
Molekulargewicht: 414.5
Reinheit: 97% (HPLC)
CAS Nummer: [1056634-68-4]
Formel: C23H22N6O2
Target-Kategorie: JAK1, JAK2, JAK3, JAK2 V617F, TYK2, CDK2, JNK1, PKD3, PKD1, ROCK2, TANK-binding kinase 1