AG-490, CAS [[133550-30-8]]

Artikelnummer: FBM-10-1091
Artikelname: AG-490, CAS [[133550-30-8]]
Artikelnummer: FBM-10-1091
Hersteller Artikelnummer: 10-1091
Alternativnummer: FBM-10-1091-5MG,FBM-10-1091-25MG
Hersteller: Focus Biomolecules
Kategorie: Biochemikalien
JAK-2 inhibitor
Molekulargewicht: 294.31
Reinheit: 98% by TLC [ 10% methanol in methylene chloride, Rf = 0.50] NMR Conforms
Formulierung: Tan solid
CAS Nummer: [133550-30-8]
Formel: C17H14N2O3
Anwendungsbeschreibung: A potent inhibitor of the JAK-2 tyrosine kinase. In acute lymphoblastic leukemia (ALL) cells, which abundantly express JAK-2, AG-490 dose-dependently blocked cell growth, induced apoptosis and inhibited DNA synthesis. Blocks the growth of all pre-B ALL c