GSK-J1, CAS [[1373422-53-7]]

Artikelnummer: FBM-10-1393
Artikelname: GSK-J1, CAS [[1373422-53-7]]
Artikelnummer: FBM-10-1393
Hersteller Artikelnummer: 10-1393
Alternativnummer: FBM-10-1393-5MG,FBM-10-1393-25MG
Hersteller: Focus Biomolecules
Kategorie: Biochemikalien
JMJ H3K27 Demethylase inhibitor (Non-cell permeable)
Molekulargewicht: 389.46
Reinheit: 99% by TLC, NMR (Conforms)
Formulierung: Pale yellow solid
CAS Nummer: [1373422-53-7]
Formel: C22H23N5O2
Anwendungsbeschreibung: Potent and selective inhibitor of jumonji H3K27 histone demethylases JMJD3 and UTX (IC50 = 60 nM, human JMJD3). This is the first known inhibitor selective for the H3K27me3-specific JMJ subfamily which binds to the active catalytic site of the enzyme. Th