Dabrafenib, CAS [[1195765-45-7]]

Produktübersicht

• Artikelname: Dabrafenib, CAS [[1195765-45-7]]
• Artikelnummer: FBM-10-1569
• Hersteller Artikelnummer: 10-1569
• Alternativnummer: FBM-10-1569-5MG,FBM-10-1569-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: GSK2118436

Produktbeschreibung

B-Raf mutant inhibitor

Produkteigenschaften

• Molekulargewicht: 519.56
• Reinheit: 98% by TLC, NMR (Conforms)
• Formulierung: Off-white solid
• CAS Nummer: [1195765-45-7]
• Formel: C23H20F3N5O2S

Anwendungsbeschreibung

• Anwendungsbeschreibung: Dabrafenib is a selective inhibitor of mutant B-RafV600E (IC50 = 0.8 nM), with 4- and 6-fold reduced potency against wild type B-Raf and c-Raf (IC50 = 3.2 and 5 nM, respectively).1 Has been in clinical trials in patients with B-RafV600E metastatic melano