Bosutinib, CAS [[380843-75-4]]

Produktübersicht

• Artikelname: Bosutinib, CAS [[380843-75-4]]
• Artikelnummer: FBM-10-2122
• Hersteller Artikelnummer: 10-2122
• Alternativnummer: FBM-10-2122-5MG,FBM-10-2122-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: SKI-606

Produktbeschreibung

Dual Src/Abl kinase inhibitor

Produkteigenschaften

• Molekulargewicht: 530.45
• Reinheit: >98% by HPLC, NMR (Conforms)
• Formulierung: Off-white solid
• CAS Nummer: [380843-75-4]
• Formel: C26H29Cl2N5O3

Anwendungsbeschreibung

• Anwendungsbeschreibung: An ATP-competitive dual Src/Abl kinase inhibitor (IC50 = 1 nM).1 It potently inhibits the apoptosis-linked STE20 kinases but does not inhibit Kit or PDGFR.2 Bosutinib was found to inhibit 16 of 18 imatinib-resistant mutant forms of Bcr-Abl expressed in m