Pazopanib, CAS [[444731-52-6]]

Artikelnummer: FBM-10-2158
Artikelname: Pazopanib, CAS [[444731-52-6]]
Artikelnummer: FBM-10-2158
Hersteller Artikelnummer: 10-2158
Alternativnummer: FBM-10-2158-10MG,FBM-10-2158-50MG
Hersteller: Focus Biomolecules
Kategorie: Biochemikalien
Alternative Synonym: GSK-VEG10003, GW786034B
Multi-receptor tyrosine kinase inhibitor
Molekulargewicht: 437.52
Reinheit: >98% by HPLC NMR (Conforms)
Formulierung: White to off-white solid
CAS Nummer: [444731-52-6]
Formel: C21H23N7O2S
Anwendungsbeschreibung: Inhibits multiple receptor tyrosine kinases including VEGFR1,2 and 3 (IC50s=10, 30, 47 nM respectively) and PDGFRalpha, beta and c-Kit (IC50s=71, 84, 74 nM respectively) and others such as FGFR.1 The drug targets both the tumor and endothelial cells in a mouse