Sorafenib (base), CAS [[284461-73-0]]
Artikelnummer:
FBM-10-2174
Artikelname: |
Sorafenib (base), CAS [[284461-73-0]] |
Artikelnummer: |
FBM-10-2174 |
Hersteller Artikelnummer: |
10-2174 |
Alternativnummer: |
FBM-10-2174-10MG,FBM-10-2174-50MG |
Hersteller: |
Focus Biomolecules |
Kategorie: |
Biochemikalien |
Alternative Synonym: |
BAY 43-9006 |
Raf-1 inhibitor (and other kinases) |
Molekulargewicht: |
464.83 |
Reinheit: |
99% by TLC, NMR (Conforms) |
Formulierung: |
Off-white solid |
CAS Nummer: |
[284461-73-0] |
Formel: |
C21H16ClF3N4O3 |
Anwendungsbeschreibung: |
Initially developed as a Raf kinase inhibitor, IC50 = 6 nM, but has been shown to inhibit many receptor tyrosine kinases including BRAF (IC50 = 22 nM), VEGFR-2 (IC50 = 90 nM), VEGFR-3 (IC50 = 20 nM), PDGFR-beta (IC50 = 57 nM), Flt3 (IC50 = 58 nM), c-KIT (IC |