Tranilast is an anti-allergy agent (inhibition of mast cell degranulation) that has been shown to have potent immunomodulatory effects (via inhibition of endotoxin induced: PGE2, IC50 = 1-20 µM, TXB2, IC50 = 10-50 µM, TGFbeta1, IC50 = 100-200 µM, IL-8, IC50
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