Topotecan HCl, CAS [[119413-54-6]]

Artikelnummer: FBM-10-2479
Artikelname: Topotecan HCl, CAS [[119413-54-6]]
Artikelnummer: FBM-10-2479
Hersteller Artikelnummer: 10-2479
Alternativnummer: FBM-10-2479-10MG,FBM-10-2479-50MG
Hersteller: Focus Biomolecules
Kategorie: Biochemikalien
Alternative Synonym: NSC 609669, SKF-104864A
DNA topoisomerase I inhibitor
Molekulargewicht: 457.91
Reinheit: >98% by HPLC NMR (Conforms)
Formulierung: Yellow solid
CAS Nummer: [119413-54-6]
Formel: C23H23N3O5 HCl
Anwendungsbeschreibung: Topotecan HCl is a water-soluble and orally active analog of camptothecin, a DNA topoisomerase I inhibitor.1 Inhibits topoisomerase I in human MCF-7 breast and DU-145 prostate cancer cells, IC50s = 13 and 2 nM respectively.2 Downregulates B-Myb and MycN