Crizotinib, CAS [[877399-52-5]]

Artikelnummer: FBM-10-2626
Artikelname: Crizotinib, CAS [[877399-52-5]]
Artikelnummer: FBM-10-2626
Hersteller Artikelnummer: 10-2626
Alternativnummer: FBM-10-2626-5MG,FBM-10-2626-25MG
Hersteller: Focus Biomolecules
Kategorie: Biochemikalien
Alternative Synonym: PF-02341066, PF-1066
c-Met and ALK inhibitor
Molekulargewicht: 450.34
Reinheit: 98% by HPLC, NMR (Conforms)
Formulierung: White solid
CAS Nummer: [877399-52-5]
Formel: C21H22Cl2FN5O
Anwendungsbeschreibung: A potent and selective inhibitor of c-MET and ALK, IC50s=8 and 20 nM respectively.1 Inhibition of cell proliferation was associated with G1-S phase cell cycle arrest and induction of apoptosis in ALK-positive ALCL cells (IC50=30 nM) but not in ALK-negati