Cabozantinib, CAS [[849217-68-1]]

Produktübersicht

• Artikelname: Cabozantinib, CAS [[849217-68-1]]
• Artikelnummer: FBM-10-3231
• Hersteller Artikelnummer: 10-3231
• Alternativnummer: FBM-10-3231-5MG,FBM-10-3231-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: XL-184, BMS-907351,

Produktbeschreibung

Met and VEGFR2 inhibitor

Produkteigenschaften

• Molekulargewicht: 501.51
• Reinheit: 98% by HPLC, NMR (Conforms)
• Formulierung: White solid
• CAS Nummer: [849217-68-1]
• Formel: C28H24FN3O5

Anwendungsbeschreibung

• Anwendungsbeschreibung: Novel inhibitor of c-met and VEGFR2 kinase activity, IC50=3.5 nm and 35 pM respectively.1 Inhibits MET-activating kinase domain mutations Y1248H, D1246N or K1262R, IC50=3.8, 11.8 and 14.6 nM respectively. In cellular assays it inhibits the following kina