Potent inhibitor glutamate carboxypeptidases II and III
Molekulargewicht:
304.30
Reinheit:
98% by HPLC NMR (Conforms)
Formulierung:
White solid
CAS Nummer:
[723331-20-2]
Formel:
C12H20N2O7
Anwendungsbeschreibung:
ZJ43 is potent inhibitor of glutamate carboxypeptidases II (Ki = 0.8 nM) and III (Ki = 23 nM).1 It blocks MDA-MB-468 cell growth with an IC50 = 3.4 nM without effecting normal cells.1 It potently (IC50 = 2.4 nM) inhibited the ability of glutamate carboxy
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