AMG 510, CAS [[2296729-00-3]]

Produktübersicht

• Artikelname: AMG 510, CAS [[2296729-00-3]]
• Artikelnummer: FBM-10-3930
• Hersteller Artikelnummer: 10-3930
• Alternativnummer: FBM-10-3930-5MG,FBM-10-3930-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Sotorasib

Produktbeschreibung

Covalent KRASG12C Inhibitor

Produkteigenschaften

• Molekulargewicht: 560.61
• Reinheit: >98% by HPLC , NMR (Conforms)
• Formulierung: White solid
• CAS Nummer: [2296729-00-3]
• Formel: C30H30F2N6O3

Anwendungsbeschreibung

• Anwendungsbeschreibung: AMG 510 is a potent (IC50s = 6 nM NCI-H358, 9 nM MIA PaCa-2) covalent KRASG12C inhibitor.1,2 It significantly inhibited tumor growth in NCI-H358 and MIA PaCa-2 cell lines as well as CT-26 tumors (mouse syngeneic model) and caused tumor regression at hig