SP100030, CAS [[154563-54-9]]

Artikelnummer: FBM-10-3996
Artikelname: SP100030, CAS [[154563-54-9]]
Artikelnummer: FBM-10-3996
Hersteller Artikelnummer: 10-3996
Alternativnummer: FBM-10-3996-5MG, FBM-10-3996-25MG
Hersteller: Focus Biomolecules
Kategorie: Biochemikalien
Alternative Synonym: 2-Chloro-4-(trifluoromethyl)pyrimidine-5-N-(3,5-bis(trifluoromethyl)phenyl)carboxamide
Dual NF-kB / AP-1 inhibitor
Molekulargewicht: 437.65
Reinheit: >98% by HPLC, NMR (conforms)
Formulierung: Off-white solid
CAS Nummer: [154563-54-9]
Formel: C14H5ClF9N3O
Anwendungsbeschreibung: SP100030 is a potent dual inhibitor of NF-kB- and AP-1-mediated gene expression (IC50s = 50 nM for both in transfected Jurkat T-cells).1 It was able to specifically block IL-2 and IL-8 in Jurkat T-cells (IC50s = 30 nM for both).1 SP100030 treatment sig