URMC-099, CAS [[1229582-33-5]]

Produktübersicht

• Artikelname: URMC-099, CAS [[1229582-33-5]]
• Artikelnummer: FBM-10-4012
• Hersteller Artikelnummer: 10-4012
• Alternativnummer: FBM-10-4012-5MG,FBM-10-4012-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien

Produktbeschreibung

Mixed-lineage kinase 3 inhibitor

Produkteigenschaften

• Molekulargewicht: 421.54
• Reinheit: 98% by TLC NMR (Conforms)
• Formulierung: Off-white solid
• CAS Nummer: [1229582-33-5]
• Formel: C27H27N5

Anwendungsbeschreibung

• Anwendungsbeschreibung: URMC-099 is a potent (IC50 = 14 nM), brain penetrant mixed-lineage kinase 3 inhibitor (MLK3). It also potently inhibits FLT3 (4 nM in vitro, but 560 nM in vivo), LRRK2 (11 nM), and ABL1 (3 nM).1 URMC-099 displayed neuroprotective effects in HIV-associate