PF-4136309, CAS [[1341224-83-6]]

Produktübersicht

• Artikelname: PF-4136309, CAS [[1341224-83-6]]
• Artikelnummer: FBM-10-4261
• Hersteller Artikelnummer: 10-4261
• Alternativnummer: FBM-10-4261-5MG,FBM-10-4261-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: INCB8761

Produktbeschreibung

CCR2 antagonist

Produkteigenschaften

• Molekulargewicht: 568.60
• Reinheit: 98% by HPLC NMR (Conforms)
• Formulierung: Off-white solid
• CAS Nummer: [1341224-83-6]
• Formel: C29H31F3N6O3

Anwendungsbeschreibung

• Anwendungsbeschreibung: PF-4136309 (1341224-83-6) is a potent (hIC50 = 5.2 nM, mIC50 = 13 nM, rIC50 = 17 nM) and selective inhibitor of CCR2.1 PF-4136309 significantly decreased inflammatory monocytes in a mouse model of pancreatic cancer.2 In combination therapy with the FOLFI