TH257, CAS [[2244678-29-1]]

Produktübersicht

• Artikelname: TH257, CAS [[2244678-29-1]]
• Artikelnummer: FBM-10-4418
• Hersteller Artikelnummer: 10-4418
• Alternativnummer: FBM-10-4418-5MG,FBM-10-4418-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien

Produktbeschreibung

Allosteric LIM kinase inhibitor

Produkteigenschaften

• Molekulargewicht: 422.54
• Reinheit: >98% by HPLC NMR (Conforms)
• Formulierung: White to off-white glassy solid
• CAS Nummer: [2244678-29-1]
• Formel: C24H26N2O3S

Anwendungsbeschreibung

• Anwendungsbeschreibung: TH257 is a potent (IC50s = 238 nM (LIMK1) and 91 nM (LIMK2)) and highly selective (no off-targets against 468 kinases) allosteric inhibitor of LIM kinase 1/2.1 It inhibited neurite outgrowth in N1E-115 cells in a dose-dependent manner.