7-Cl-O-Nec1, CAS [[852391-15-2]]

Artikelnummer: FBM-10-4544
Artikelname: 7-Cl-O-Nec1, CAS [[852391-15-2]]
Artikelnummer: FBM-10-4544
Hersteller Artikelnummer: 10-4544
Alternativnummer: FBM-10-4544-5MG,FBM-10-4544-25MG
Hersteller: Focus Biomolecules
Kategorie: Biochemikalien
Alternative Synonym: Nec-1s, Necrostatin1-S
Rip1 blocker
Molekulargewicht: 277.71
Reinheit: 98% by TLC (5% methanol / methylene chloride, Rf = 0.55), NMR (Conforms)
Formulierung: Yellow solid
CAS Nummer: [852391-15-2]
Formel: C13H12ClN3O2
Anwendungsbeschreibung: Necrostatin-1 analogue with superior potency (IC50 = 206nM vs 494nM), selectivity and metabolic stability in blocking RIP1.1,2 7-Cl-O-Nec-1 shows no off-target inhibition of indolamine-2,3-deoxygenase (IDO) in contrast to Necrostatin-1 (Nec-1).3,4 7-Cl-O