AGI-5198, CAS [[1355326-35-0]]

Produktübersicht

• Artikelname: AGI-5198, CAS [[1355326-35-0]]
• Artikelnummer: FBM-10-4599
• Hersteller Artikelnummer: 10-4599
• Alternativnummer: FBM-10-4599-5MG,FBM-10-4599-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien

Produktbeschreibung

R132 mutant isocitrate dehydrogenase inhibitor

Produkteigenschaften

• Molekulargewicht: 462.56
• Reinheit: 98% by HPLC, NMR (Conforms)
• Formulierung: White solid
• CAS Nummer: [1355326-35-0]
• Formel: C27H31FN4O2

Anwendungsbeschreibung

• Anwendungsbeschreibung: AGI-5198 is a potent (IC50 = 70 nM) inhibitor of mutant isocitrate dehydrogenase 1(IDH1).1 It is selective for the R132H-IDH1 mutant and does not affect wild type cells.2 This mutation results in loss-of-function for oxidative decarboxylation of isocitra