Necrostatin-34, CAS [[375835-43-1]]

Produktübersicht

• Artikelname: Necrostatin-34, CAS [[375835-43-1]]
• Artikelnummer: FBM-10-4684
• Hersteller Artikelnummer: 10-4684
• Alternativnummer: FBM-10-4684-5MG,FBM-10-4684-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Nec-34, 2-((3-Cyano-6-oxo-4-(p-tolyl)-1,4,5,6-tetrahydropyridin-2-yl)thio)-N-(thiazol-2-yl)acetamide

Produktbeschreibung

RIP1 kinase inhibitor

Produkteigenschaften

• Molekulargewicht: 384.47
• Reinheit: >98% by HPLC NMR (Conforms)
• Formulierung: Off-white solid
• CAS Nummer: [375835-43-1]
• Formel: C18H16N4O2S2

Anwendungsbeschreibung

• Anwendungsbeschreibung: Necrostatin-34 is a selective inhibitor of RIP1 kinase. IC50s = 667 nM and 134 nM for TNFalpha in FAD-deficient Jurkat cells and L929 cells respectively. It binds to a site distinct from that of 7-Cl-O-Nec1 (Focus Cat 10-4544) locking the enzyme in an inact