99% by HPLC (Agilent Poroshell 120 C18, 80/20 MeOH/water with 0.05% TFA, 0.8 ml/min) NMR (Conforms)
Formulierung:
Orange-yellow solid
CAS Nummer:
[1062368-62-0]
Formel:
C25H22N62HCl
Anwendungsbeschreibung:
LDN-193189 HCl is a potent and selective inhibitor of ALK2 (IC50 = 5 nM) and ALK3 (IC50 = 30 nM), thereby inhibiting SMAD1/5/8 phosphorylation.1 Only weak inhibition of ALK4, ALK5, and ALK7 is observed. Promotes neuronal differentiation of human pluripot
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