LDN-193189 HCl, CAS [[1062368-62-0]]

Artikelnummer: FBM-10-4764
Artikelname: LDN-193189 HCl, CAS [[1062368-62-0]]
Artikelnummer: FBM-10-4764
Hersteller Artikelnummer: 10-4764
Alternativnummer: FBM-10-4764-5MG,FBM-10-4764-25MG
Hersteller: Focus Biomolecules
Kategorie: Biochemikalien
Alternative Synonym: DM-3189
ALK2 / ALK3 inhibitor
Molekulargewicht: 479.4
Reinheit: 99% by HPLC (Agilent Poroshell 120 C18, 80/20 MeOH/water with 0.05% TFA, 0.8 ml/min) NMR (Conforms)
Formulierung: Orange-yellow solid
CAS Nummer: [1062368-62-0]
Formel: C25H22N62HCl
Anwendungsbeschreibung: LDN-193189 HCl is a potent and selective inhibitor of ALK2 (IC50 = 5 nM) and ALK3 (IC50 = 30 nM), thereby inhibiting SMAD1/5/8 phosphorylation.1 Only weak inhibition of ALK4, ALK5, and ALK7 is observed. Promotes neuronal differentiation of human pluripot