MTX-531, CAS [[2791417-66-6]]

Produktübersicht

• Artikelname: MTX-531, CAS [[2791417-66-6]]
• Artikelnummer: FBM-10-4802
• Hersteller Artikelnummer: 10-4802
• Alternativnummer: FBM-10-4802-5MG,FBM-10-4802-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien

Produktbeschreibung

Dual EGFR/PI3K inhibitor

Produkteigenschaften

• Molekulargewicht: 453.95
• Reinheit: >98% by HPLC NMR (Conforms)
• Formulierung: White solid
• CAS Nummer: [2791417-66-6]
• Formel: C22H20ClN5O2S

Anwendungsbeschreibung

• Anwendungsbeschreibung: MTX-531 is a first-in-class dual EGFR/pan-PI3K inhibitor (IC50s: EGFR = 14.7 nM, PI3kalpha = 6.4 nM, PI3Kß = 233 nM, PI3Kgamma = 8.3 nM, PI3Kdelta = 1.1 nM, mTOR = 105 nM, DNA-PK = 5.4 nM). MTX-531 displayed exquisite selectivity for EGFR and PI3K family members (ag