Defactinib, CAS [[1073154-85-4]]

Produktübersicht

• Artikelname: Defactinib, CAS [[1073154-85-4]]
• Artikelnummer: FBM-10-4828
• Hersteller Artikelnummer: 10-4828
• Alternativnummer: FBM-10-4828-5MG,FBM-10-4828-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: PF-04554878

Produktbeschreibung

FAK inhibitor

Produkteigenschaften

• Molekulargewicht: 510.50
• Reinheit: 98% by HPLC NMR (Conforms)
• Formulierung: White solid
• CAS Nummer: [1073154-85-4]
• Formel: C20H21F3N8O3S

Anwendungsbeschreibung

• Anwendungsbeschreibung: Defactinib (1073154-85-4) is a potent inhibitor of FAK (IC50 = 0.6nM) and Pyk2 (IC50 = 0.6nM).1 It is active in vivo (EC50 = 26nM). FAK inhibition prevents tumor invasion and dissemination rather than tumor size reduction. Defactinib has been shown to pr