Larotrectinib, CAS [[1223403-58-4]]

Produktübersicht

• Artikelname: Larotrectinib, CAS [[1223403-58-4]]
• Artikelnummer: FBM-10-4832
• Hersteller Artikelnummer: 10-4832
• Alternativnummer: FBM-10-4832-5MG,FBM-10-4832-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: LOXO-101, ARRY-470

Produktbeschreibung

panTRK inhibitor

Produkteigenschaften

• Molekulargewicht: 428.44
• Reinheit: 98% by HPLC NMR (Conforms)
• Formulierung: Yellow solid
• CAS Nummer: [1223403-58-4]
• Formel: C21H22F2N6O2

Anwendungsbeschreibung

• Anwendungsbeschreibung: Larotrectinib is a potent (IC50s < 11 nM) inhibitor of tropomyosin receptor kinases A, B, and C (TrkA, B, and C).1 It is >100 fold selective against a panel of 229 kinases. Larotrectinib markedly attenuated bone cancer pain and significantly blocked the