NDI-091143, CAS [[2375840-87-0]]
Artikelnummer:
FBM-10-4841
Artikelname: |
NDI-091143, CAS [[2375840-87-0]] |
Artikelnummer: |
FBM-10-4841 |
Hersteller Artikelnummer: |
10-4841 |
Alternativnummer: |
FBM-10-4841-5MG,FBM-10-4841-25MG |
Hersteller: |
Focus Biomolecules |
Kategorie: |
Biochemikalien |
Potent allosteric ATP-citrate lyase inhibitor |
Molekulargewicht: |
453.84 |
Reinheit: |
>98% by HPLC NMR (Conforms) |
Formulierung: |
Off-white solid |
CAS Nummer: |
[2375840-87-0] |
Formel: |
C20H14ClF2NO5S |
Anwendungsbeschreibung: |
Potent (IC50 = 2.1 nM ADP-Glo assay, 4.8 nM Oxaloacetate coupled enzyme assay) allosteric inhibitor of ATP-citrate lyase.1 NDI-091143 suppressed growth and clonogenic ability in thyroid cancer cell lines FTC-133 and 8505C.2 It also synergistically potent |